Assessment of idiopathic rapid‐eye‐movement sleep behavior disorder by transcranial sonography, olfactory function test, and FP‐CIT‐SPECT
Identifieur interne : 002991 ( Main/Exploration ); précédent : 002990; suivant : 002992Assessment of idiopathic rapid‐eye‐movement sleep behavior disorder by transcranial sonography, olfactory function test, and FP‐CIT‐SPECT
Auteurs : Marcus M. Unger [Allemagne] ; Jens C. Möller [Allemagne] ; Karin Stiasny-Kolster [Allemagne] ; Katharina Mankel [Allemagne] ; Daniela Berg [Allemagne] ; Uwe Walter [Allemagne] ; Helmut Hoeffken [Allemagne] ; Geert Mayer [Allemagne] ; Wolfgang H. Oertel [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-03-15.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Aged, Behavior, Cognition Disorders (diagnosis), Cognition Disorders (epidemiology), Humans, Idiopathic, Locus niger, Male, Middle Aged, Nervous system diseases, Neuropsychological Tests, Olfaction Disorders (diagnosis), Olfaction Disorders (epidemiology), Olfaction Disorders (physiopathology), Olfactory disorder, Parkinson disease, Parkinson's disease, Photon, REM Sleep Behavior Disorder (diagnosis), REM Sleep Behavior Disorder (epidemiology), Radiopharmaceuticals (diagnostic use), Rapid eye movement sleep, Severity of Illness Index, Single photon emission tomography, Sonography, Substantia Nigra (metabolism), Substantia Nigra (physiopathology), Substantia Nigra (ultrasonography), Tomography, Emission-Computed, Single-Photon, Tropanes (diagnostic use), Ultrasonography, Doppler, Transcranial (methods), rapid‐eye‐movement sleep behavior disorder, substantia nigra hyperechogenicity, transcranial sonography.
- MESH :
- chemical , diagnostic use : Radiopharmaceuticals, Tropanes.
- diagnosis : Cognition Disorders, Olfaction Disorders, REM Sleep Behavior Disorder.
- epidemiology : Cognition Disorders, Olfaction Disorders, REM Sleep Behavior Disorder.
- metabolism : Substantia Nigra.
- methods : Ultrasonography, Doppler, Transcranial.
- physiopathology : Olfaction Disorders, Substantia Nigra.
- ultrasonography : Substantia Nigra.
- Aged, Humans, Male, Middle Aged, Neuropsychological Tests, Severity of Illness Index, Tomography, Emission-Computed, Single-Photon.
Abstract
Idiopathic rapid‐eye‐movement (REM) sleep behavior disorder (iRBD) has been suggested to be a risk factor for subsequent development of neurodegenerative disorders, especially Parkinson's disease (PD) and other α‐synucleinopathies. At present, it is not possible to predict whether or not an iRBD patient will eventually develop PD. Here, we report 5 iRBD patients who underwent a test battery comprising a neurological examination (including UPDRS rating), mini mental state examination testing, transcranial sonography, olfactory function testing, and presynaptic dopamine transporter imaging with FP‐CIT‐SPECT. Our preliminary data show the diverse pattern of individual combinations of pathological findings when a multimodal assessment approach is applied in this patient group. Large‐size longitudinal studies in iRBD patients are required to evaluate the usefulness of diagnostic tests to identify the subgroup of iRBD patients that is prone to develop PD. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21908
Affiliations:
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At present, it is not possible to predict whether or not an iRBD patient will eventually develop PD. Here, we report 5 iRBD patients who underwent a test battery comprising a neurological examination (including UPDRS rating), mini mental state examination testing, transcranial sonography, olfactory function testing, and presynaptic dopamine transporter imaging with FP‐CIT‐SPECT. Our preliminary data show the diverse pattern of individual combinations of pathological findings when a multimodal assessment approach is applied in this patient group. Large‐size longitudinal studies in iRBD patients are required to evaluate the usefulness of diagnostic tests to identify the subgroup of iRBD patients that is prone to develop PD. © 2007 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Allemagne</li></country></list><tree><country name="Allemagne"><noRegion><name sortKey="Unger, Marcus M" sort="Unger, Marcus M" uniqKey="Unger M" first="Marcus M." last="Unger">Marcus M. Unger</name></noRegion><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name><name sortKey="Hoeffken, Helmut" sort="Hoeffken, Helmut" uniqKey="Hoeffken H" first="Helmut" last="Hoeffken">Helmut Hoeffken</name><name sortKey="Mankel, Katharina" sort="Mankel, Katharina" uniqKey="Mankel K" first="Katharina" last="Mankel">Katharina Mankel</name><name sortKey="Mayer, Geert" sort="Mayer, Geert" uniqKey="Mayer G" first="Geert" last="Mayer">Geert Mayer</name><name sortKey="Moller, Jens C" sort="Moller, Jens C" uniqKey="Moller J" first="Jens C." last="Möller">Jens C. Möller</name><name sortKey="Oertel, Wolfgang H" sort="Oertel, Wolfgang H" uniqKey="Oertel W" first="Wolfgang H." last="Oertel">Wolfgang H. Oertel</name><name sortKey="Stiasny Olster, Karin" sort="Stiasny Olster, Karin" uniqKey="Stiasny Olster K" first="Karin" last="Stiasny-Kolster">Karin Stiasny-Kolster</name><name sortKey="Walter, Uwe" sort="Walter, Uwe" uniqKey="Walter U" first="Uwe" last="Walter">Uwe Walter</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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